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The Sidney Kimmel Foundation for Cancer Research Announces 2014 Grant Recipients

PHILADELPHIA, April 22, 2013 –The Sidney Kimmel Foundation for Cancer Research has selected the 2014 recipients for the Kimmel Scholar Program. Fifteen research scientists and medical doctors from across the United States will receive two year grants totaling $200,000 under the Foundation's on-going Kimmel Scholar program. This year's selection brings the total to 247 talented cancer researchers who have been provided with grant money since the Foundation's inception.

The Kimmel Scholar Awards were created to advance the careers of gifted, young scientists involved in cancer research. Those selected are chosen for demonstrating the greatest promise and innovation in their work, must be in the early stages of their research career, and have not progressed far enough to have received major grants from the National Cancer Institute or other funding sources.

Sidney Kimmel, the organization's namesake, founder of The Jones Group Inc., and president of Sidney Kimmel Entertainment, meets each year with the Foundation's medical advisory board as the esteemed group of leading cancer doctors narrows down the applicants from a pool of approximately 150. Since 1997 Sidney Kimmel has contributed more than $550 million to cancer centers and cancer research and another $100 million to the arts and Jewish continuity. Kimmel is a member of Warren Buffett's Giving Pledge, having already committed more than half of his net worth to charitable causes.

Many of the exceptional young scientists who have their careers "jump started" by the Sidney Kimmel Foundation for Cancer Research go on to receive millions of dollars in funding from the NCI and NIH and make significant contributions to the field of cancer research. Many report that they might never have achieved such success without first receiving a Kimmel grant.

The recipients for 2014 are:             

·         Karim-Jean Armache, PhD

New York University

“Structure and mechanism of PRC2 in health and cancer”

·         *Kathrin Bernt, MD

University of Colorado, Denver

“Epigenetic targeting of MN1-high, poor prognosis acute myeloid leukemia”

·         *Ryan Fields, MD

Washington University, St. Louis

“Improving outcomes in metastatic colorectal cancer – A comprehensive genomic, transcriptomic, epigenetic, and metabolomic profiling of matched primary and metastatic colorectal cancer specimens”

·         Viviana Gradinaru, PhD

California Institute of Technology

“Optical switches for spatially and temporally precise cancer interrogation”

·         Mitchell Guttman, PhD

California Institute of Technology

“Uncovering principles of large non-coding RNA regulatory specificity in cancer”

·         Andrew Holland, PhD

Johns Hopkins University School of Medicine

“Exploring and exploiting centrosome amplification in hematological malignancies”

·         *Mohit Jain, MD, PhD

University of California, San Diego

“Comprehensive reconstruction of global metabolic enzyme activity in-vivo in human cancer”

·         *Filip Janku, MD, PhD

University of Texas, MD Anderson

“Liquid Biopsies in advanced cancers with V600 BRAF mutations”

·         Kitai Kim, PhD

Memorial Sloan-Kettering Cancer Center

 “Aging associated oncogenic epigenetic signatures in induced pluripotent stem cells”

·         *James Kim, MD, PhD

University of Texas, Southwestern

“The interaction of stromal hedgehog pathway with cancer stem cells of lung adenocarcinoma”

·         Alexei Korennykh, PhD

Princeton University

“Systems biology of interferon activated RNA decay in cancer metastasis”

·         Shannon Lauberth, PhD

University of California, San Diego

“Understanding the role of epigenetic alterations in the deregulation of gene expression in human colorectal carcinoma”

·         Sabine Petry, PhD

Princeton University

“Molecular basis of the chromosome segregation machinery and its malfunction”

·         Gang Wang, PhD

University of North Carolina, Chapel Hill

“Deciphering the role of histone demethylation in hematopoietic malignancies”

·         Qing Zhang, PhD

University of North Carolina, Chapel Hill

“Determining the regulation of progesterone receptor (PR) by EgIN2 in tamoxifen resistant breast cancer”

*Translational Research

 

The Foundation is particularly interested in helping physicians who are engaged in research which can rapidly be translated into benefits for patients with cancer.  This year five of the fifteen awards have been designated for such "Translational Research."

The Sidney Kimmel Foundation for Cancer Research has also funded cancer centers at Memorial Sloan-Kettering Cancer Center, Thomas Jefferson University and Johns Hopkins University. The gift to Johns Hopkins, $150 million, is the largest gift ever received by that institution. In the area of arts and culture, The Kimmel Foundation has supported the Kimmel Center for the Performing Arts and National Museum of American Jewish History in Philadelphia as well as the United States Holocaust Memorial Museum in Washington D.C., among others. For more information visit www.kimmel.org.

 

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The Sidney Kimmel Foundation For Cancer Research Announces 2013 Grant Recipients

For Immediate Release
Contact:  Risa B. Hoag @ 845-627-3000 or risa@kimmel.org

PHILADELPHIA, May 10, 2013 –The Sidney Kimmel Foundation for Cancer Research has selected the 2013 recipients for the Kimmel Scholar Program. Fifteen research scientists and medical doctors from across the United States will receive two year grants totaling $200,000 under the Foundation's on-going Kimmel Scholar program. This year's selection brings the total to 232 talented cancer researchers who have been provided with grant money since the Foundation's inception.

The Kimmel Scholar Awards were created to advance the careers of gifted, young scientists involved in cancer research. Those selected are chosen for demonstrating the greatest promise and innovation in their work, must be in the early stages of their research career, and have not progressed far enough to have received major grants from the National Cancer Institute or other funding sources.

Sidney Kimmel, the organization's founder, chairman of Jones Group and president of Sidney Kimmel Entertainment, meets each year with the Foundation's medical advisory board and observes as the esteemed group of leading cancer doctors narrows down the applicants from a pool of approximately 150. Since 1997 Sidney Kimmel has contributed more than $550 million to cancer centers and cancer research and another $100 million to the arts and Jewish continuity. Kimmel is a member of Warren Buffett's Giving Pledge having already committed more than half of his net worth to charitable causes.

Many of the exceptional young scientists who have their careers jump started by the Sidney Kimmel Foundation for Cancer Research go on to receive millions of dollars in funding from the NCI and NIH and make significant contributions to the field of cancer research. Many report that they might never have achieved such success without first receiving a Kimmel grant.

The recipients for 2013 are:   

Michael Boyce, Ph.D.
Duke University Medical Center
“Dissecting the role of O-GlcNAc in cancer cell metabolism”

*Lauren Byers, M.D., M.S.
University of Texas, MD Anderson Cancer Center
“Co-targeting of PARP1 and the PI3K pathway in small cell lung cancer”

*Darren Carpizo, M.D., Ph.D.
The Cancer Institute of New Jersey
“Exploration of Thiosemicarbazones as mutant p53 reactivators”

 

Craig Ceol, Ph.D.
University of Massachusetts Medical School
“Use of comparative genomics to identify novel regulators of melanoma progression”

Sophie Dumont, Ph.D.
University of California, San Francisco
"
Uncovering the mechanical design principles of accurate chromosome segregation”

Dorothea Fiedler, Ph.D.
Princeton University
“Understanding phosphate metabolism in cancer and metastasis”

Evripidis Gavathiotis, Ph.D.
Albert Einstein College of Medicine
“Direct targeting of pro-apoptotic BAX as a therapeutic strategy to restore cancer cell death”

*Puneeth Iyengar, M.D., Ph.D.
UT Southwestern Medical Center – Dallas
“Development of a genomic signature for predicting cachexia-inducing tumors to facilitate early therapeutic intervention”

Michael Kharas, Ph.D.
Sloan-Kettering Institute for Cancer Research
“The role of musashi-2 in myeloid leukemia”

Katja Lamia, Ph.D.
The Scripps Research Institute
“Circadian transcriptional repressors Cry1 and Cry2 modulate cell growth and transformation”

Young-Sam Lee, Ph.D.
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
“Systematic approach to discover novel allosteric regulators controlling the metabolic adaptation of cancer”

Ryan OConnell, Ph.D.
University of Utah
“Deciphering the roles of microRNAs during antitumor immunity”

*Eirini Papapetrou, M.D., Ph.D.
University of Washington
“Mining cancer genomes using directly reprogrammed and genetically engineered human pluripotent stem cells”

Matthias Stadtfeld, Ph.D.
New York University School of Medicine
“Role and mechanism of imprinted gene dysregulation in cancer”

*Phuoc Tran M.D., Ph.D.
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
“Modeling EMT-induced lung adenocarcinoma resistance to erlotinib in vivo”

* Translational Scholars

The Foundation is particularly interested in helping physicians who are engaged in research which can rapidly be translated into benefits for patients with cancer.  This year four of the fifteen awards have been designated for such "Translational Research."

The Sidney Kimmel Foundation for Cancer Research has also funded cancer centers at Memorial Sloan-Kettering Cancer Center, Thomas Jefferson University and Johns Hopkins University. The gift to Johns Hopkins, $150 million, is the largest gift ever received by that institution. In the area of arts and culture, The Kimmel Foundation has supported the Kimmel Center for the Performing Arts in Philadelphia as well as the United States Holocaust Memorial Museum in Washington D.C., among others.

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The Sidney Kimmel Foundation For Cancer Research Announces 2012 Grant Recipients

The recipients for 2012 are:             

 
Eric Bennett, Ph.D University of California San Diego
Targeting ubiquitin-proteasome system control of cellular redox homeostasis function
 
*Trever Bivona, M.D., Ph.D , University of California San Francisco
Discovery of rational companion therapeutic targets to optimize molecularly-targeted cancer therapy
 
*Ping Chi, M.D., Ph.D , Memorial Sloan-Kettering Cancer Center
Understanding and targeting the oncogenic lineage-specific transcription factor-ETV1-in gastrointestinal stromal tumor (GIST)
 
Kevin Corbett, Ph.D , Ludwig Institute for Cancer Research and University of California, San Diego
Mechanisms and regulation of homologous recombination in meiosis
 
Boyi Gan, Ph.D , The University of Texas, M.D. Anderson Cancer Center
Targeting genetic and metabolic networks in renal cell carcinoma
 
Ekaterin Grishchuk, Ph.D , University of Pennsylvania
Linking the spatial patterns of mitotic phosphoregulation and chromosomal instability in cancer cells
 
Andre Hoelz, Ph.D , California Institute ofTechnology
Structural and functional analysis of macromolecular machines in chromatin biology and carcinogenesis
 
*Jason Huse, M.D., Ph.D , Memorial Sloan-Kettering Cancer Center
Investigating miRNA networks that promote proneural gliomagenesis
 
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