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2014 Kimmel Scholar Recipients

·         Karim-Jean Armache, PhD

New York University: “Structure and mechanism of PRC2 in health and cancer”

·         *Kathrin Bernt, MD

University of Colorado, Denver:  “Epigenetic targeting of MN1-high, poor prognosis acute myeloid leukemia”

·         *Ryan Fields, MD

Washington University, St. Louis: “Improving outcomes in metastatic colorectal cancer – A comprehensive genomic, transcriptomic, epigenetic, and metabolomic profiling of matched primary and metastatic colorectal cancer specimens”

·         Viviana Gradinaru, PhD

California Institute of Technology: “Optical switches for spatially and temporally precise cancer interrogation”

·         Mitchell Guttman, PhD

California Institute of Technology:  “Uncovering principles of large non-coding RNA regulatory specificity in cancer”

·         Andrew Holland, PhD

Johns Hopkins University School of Medicine: “Exploring and exploiting centrosome amplification in hematological malignancies”

·         *Mohit Jain, MD, PhD

University of California, San Diego: “Comprehensive reconstruction of global metabolic enzyme activity in-vivo in human cancer”

·         *Filip Janku, MD, PhD

University of Texas, MD Anderson: “Liquid Biopsies in advanced cancers with V600 BRAF mutations”

·         Kitai Kim, PhD

Memorial Sloan-Kettering Cancer Center:  “Aging associated oncogenic epigenetic signatures in induced pluripotent stem cells”

·         *James Kim, MD, PhD

University of Texas, Southwester: “The interaction of stromal hedgehog pathway with cancer stem cells of lung adenocarcinoma”

·         Alexei Korennykh, PhD

Princeton University: "Systems biology of interferon activated RNA decay in cancer metastasis”

·         Shannon Lauberth, PhD

University of California, San Diego: “Understanding the role of epigenetic alterations in the deregulation of gene expression in human colorectal carcinoma”

·         Sabine Petry, PhD

Princeton University: “Molecular basis of the chromosome segregation machinery and its malfunction”

·         Gang Wang, PhD

University of North Carolina, Chapel Hill: “Deciphering the role of histone demethylation in hematopoietic malignancies”

·         Qing Zhang, PhD

University of North Carolina, Chapel Hill: “Determining the regulation of progesterone receptor (PR) by EgIN2 in tamoxifen resistant breast cancer”

*Translational Research

 

2013 Kimmel Scholar Recipients

Michael Boyce, Ph.D.
Duke University Medical Center
“Dissecting the role of O-GlcNAc in cancer cell metabolism”

*Lauren Byers, M.D., M.S.
University of Texas, MD Anderson Cancer Center
“Co-targeting of PARP1 and the PI3K pathway in small cell lung cancer”

*Darren Carpizo, M.D., Ph.D.
The Cancer Institute of New Jersey
“Exploration of Thiosemicarbazones as mutant p53 reactivators”

Craig Ceol, Ph.D.
University of Massachusetts Medical School
“Use of comparative genomics to identify novel regulators of melanoma progression”

Sophie Dumont, Ph.D.
University of California, San Francisco
"
Uncovering the mechanical design principles of accurate chromosome segregation”

Dorothea Fiedler, Ph.D.
Princeton University
“Understanding phosphate metabolism in cancer and metastasis”

Evripidis Gavathiotis, Ph.D.
Albert Einstein College of Medicine
“Direct targeting of pro-apoptotic BAX as a therapeutic strategy to restore cancer cell death”

*Puneeth Iyengar, M.D., Ph.D.
UT Southwestern Medical Center – Dallas
“Development of a genomic signature for predicting cachexia-inducing tumors to facilitate early therapeutic intervention”

Michael Kharas, Ph.D.
Sloan-Kettering Institute for Cancer Research
“The role of musashi-2 in myeloid leukemia”

Katja Lamia, Ph.D.
The Scripps Research Institute
“Circadian transcriptional repressors Cry1 and Cry2 modulate cell growth and transformation”

Young-Sam Lee, Ph.D.
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
“Systematic approach to discover novel allosteric regulators controlling the metabolic adaptation of cancer”

Ryan OConnell, Ph.D.
University of Utah
“Deciphering the roles of microRNAs during antitumor immunity”

*Eirini Papapetrou, M.D., Ph.D.
University of Washington
“Mining cancer genomes using directly reprogrammed and genetically engineered human pluripotent stem cells”

Matthias Stadtfeld, Ph.D.
New York University School of Medicine
“Role and mechanism of imprinted gene dysregulation in cancer”

*Phuoc Tran M.D., Ph.D.
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
“Modeling EMT-induced lung adenocarcinoma resistance to erlotinib in vivo”

* Translational Scholars




2012 KIMMEL SCHOLAR RECIPIENTS          
 
Eric Bennett, Ph.D., University of California, San Diego
Targeting ubiquitin-proteasome system control of cellular redox homeostasis function
 
*Trever Bivona, M.D., Ph.D., University of California, San Francisco
Discovery of rational companion therapeutic targets to optimize molecularly-targeted cancer therapy
 
*Ping Chi, M.D., Ph.D., Memorial Sloan-Kettering Cancer Center
Understanding and targeting the oncogenic lineage-specific transcription factor-ETV1-in gastrointestinal stromal tumor (GIST)
 
Kevin Corbett, Ph.D., Ludwig Institute for Cancer Research and University of California, San Diego
Mechanisms and regulation of homologous recombination in meiosis
 
Boyi Gan, Ph.D., The University of Texas, M.D. Anderson Cancer Center
Targeting genetic and metabolic networks in renal cell carcinoma
 
Ekaterina Grishchuk, Ph.D., University of Pennsylvania
Linking the spatial patterns of mitotic phosphoregulation and chromosomal instability in cancer cells
 
Andre Hoelz, Ph.D., California Institute of Technology
Structural and functional analysis of macromolecular machines in chromatin biology and carcinogenesis
 
*Jason Huse, M.D., Ph.D., Memorial Sloan-Kettering Cancer Center
Investigating miRNA networks that promote proneural gliomagenesis
 
*Chrystal  Louis, M.D., Ph.D., Baylor College of Medicine
Enhancing antitumor activity of cytotoxic t cells used to treat nasopharyngeal carcinoma
 
Li-Fan Lu, Ph.D., University of California, San Diego
Unveiling molecular mechanisms underlying miR-146a-dependent T-reg cell-mediated TH1 regulation as new targets for anti-cancer therapy
 
*Sanaz Memarzadeh, M.D., Ph.D., University of California, Los Angeles
Progesterone signaling as a regulator of hormone sensitivity in the endometrial tumor microenvironment
 
Ji-hye Paik, Ph.D., Weill Cornell Medical College
Function of FoxO in EGFR-targeted gliomas
 
Dong Wang, Ph.D., University of California, San Diego
Develop novel anticancer drugs targeting DNA damage processing pathways
 
Zhibin Wang, Ph.D., Johns Hopkins University
Abnormal epigenetic codes mediated by DNMT1 and NuRD/Mi-2 complex in cancer cells
 
*Elizabeth Wick, M.D., Johns Hopkins University, Kimmel Cancer Center
Defining enterotoxigenic bacteriodes fragilis induced genetic alterations in colorectal cancer
 
* Translational Scholars

 

2011 KIMMEL SCHOLAR AWARDEES

 

*Clark Chen, M.D., Ph.D.

Dana Farber Cancer Institute

Co-optation of G-protein coupled neurotransmitter receptor pathways in glioblastomas

 

Michela Garofalo, Ph.D.

Ohio State University

Role of Tyrosine Kinase Receptors-deregulated microRNAs in tumorigenesis and gefitinib resistance of NSCLC

 

Suzanne Gaudet, Ph.D.

Dana Farber Cancer Institute

TNF signaling dynamics and cancer cell fate determination

 

Geraldine Guasch, Ph.D.

Cincinnati Children's Hospital Medical Center

Defining the cellular origin and the signaling pathways involved in epithelial cancers of transitional epithelia

 

Min Guo, Ph.D.

The Scripps Research Institute

Lysyl-tRNA Synthetase: A Novel Regulator of MITF in Melanoma

 

Dimitrios Iliopoulos, Ph.D.

Dana Farber Cancer Institute

Identification of Novel Signaling Networks in Pancreatic Cancer Stem Cells

 
Mei Kong, Ph.D.

Targeting PP2A and the Glutamine-Sensing Pathway as Cancer Treatment

  

*Roger Lo, M.D., Ph.D.

The Regents of the University of California, Los Angeles

Exome sequencing of melanomas with acquired resistance to BRAF inhibitors

 

Christine Mayr, M.D., Ph.D.

Memorial Sloan-Kettering Cancer Center

Cause and consequences of mRNAs with heterogeneous 3' ends for the pathogenesis of cancer

*Stephen Oh, M.D., Ph.D.

Washington University School of Medicine

Functional Characterization of LNK Mutations in Myeloproliferative Neoplasms

 

*Dinesh Rao, M.D., Ph.D.

The Regents of the University of California, Los Angeles (UCLA)

Unraveling the role of microRNA in hematolymphoid malignancy

 

*Narendra Wajapeyee, Ph.D.

Yale University

Deciphering and Targeting RAS-mutant Cancers

Catherine Yan, Ph.D.

Beth Israel Deaconess Medical Center

Elucidating the Key End-Ligation Enzyme and Co-Factors Promoting Alternative DNA End-Joining

 

*Eddy Yang, M.D., Ph.D.

University of Alabama-Birmingham

Can inhibition of epidermal growth factor receptor (EGFR) signaling induce synthetic lethality with poly (ADP-Ribose) polymerase inhibition (PARPi) by generating a DNA repair defect?

 

Hongwu Zheng, Ph.D.

Cold Spring Harbor Laboratory

Genetic and functional analysis of malignant glioma cell self-renewal and differentiation

 

 

* Translational Scholars

 

2010 KIMMEL SCHOLAR AWARDEES

 

* Maximillian Diehn, M.D., Ph.D.

Stanford University School of Medicine

Exploring Metabolic Properties of Tumor Initiating Cells

 

Matthew Gamble, Ph.D.

Albert Einstein College of Medicine

Exploring the interplay between macro domains and poly (ADP-ribose) polymerases in tumor progression and suppression

 

Zev Gartner, Ph.D.

University of California, San Francisco

Unraveling the relationship between tissue structure and cancer progression

 

* Rani George, M.D., Ph.D.

Dana-Farber Cancer Institute

Functional analysis of ALK mutations in neuroblastoma

 

A. McGarry Houghton, M.D.

University of Pittsburgh

IRS1-Mediated Regulation of P13K and MEK/ERK Activity in Lung Cancer

 

Antoine Karnoub, Ph.D.

Beth Israel Deaconess Medical Center

Role of Stem Cells in the Metastatic Spread of Breast Carcinomas

 
* Alec Kimmelman, M.D., Ph.D.

Dana-Farber Cancer Institute

Defining Biomarkers of Autophagy Addiction in Human Cancers

  

Ivan Maillard, M.D., Ph.D.

University of Michigan

Role of the Ash1L histone methyltransferase in normal and malignant hematopoiesis

 

Michael Major, Ph.D.

University of North Carolina at Chapel Hill

New Functional Components of the KEAP1 Tumor Supressor Protein Complex

Ashby Morrison, Ph.D.

Stanford University

A Novel Mechanism for Tumor Suppression by the Retinoblastoma Protein

 

* Donald Parsons, M.D., Ph.D.

Baylor College of Medicine

Defining molecular subtypes of hepatoblastoma

 

Flavia Pichiorri, Ph.D.

Ohio State University

microRNAs in multiple myeloma diagnosis, prognosis and therapy

Xiaobing Shi, Ph.D.

University of Texas, M.D. Anderson Cancer Center

The roles of PHD fingers in dynamic histone lysine methylation and human cancer

 

Alexander Stegh, Ph.D.

Northwestern University

Development and Characterization of Bc12L12-driven GBM Mouse Models

 

*  Nicola Valeri, M.D.

Ohio State University

MicroRNA-mediated Modulation of genomic stability and apoptosis in sporadic and inflammatory bowel disease associated coloncancer

 

 

* Translational Scholars

 

2009 KIMMEL SCHOLAR AWARDEES

 

*Valerie Brown, M.D., Ph.D.

Children's Hospital of Philadelphia

Preclinical evaluation of targeting the mTOR signaling network in acute lymphoblastic leukemia

 

Paul Chang, Ph.D.

Massachusetts Institute of Technology

New PARP isoforms for cancer therapies

 

Lara Collier, Ph.D.

University of Wisconsin, Madison

Genetic approaches to studying glioma formation and therapy resistance

 

Muller Fabbri, M.D.

Ohio State University Research Foundation

Role of p53 regulation of microRNAs and ultraconserved regions in human cancer

 

Danica Galonic Fujimori, Ph.D.

University of California, San Francisco

Histone-modifying enzymes in cancer: elucidating roles of histone demethylases

 

* Erich Huang, M.D., Ph.D.

Duke University Medical Center

Oncogenic network interrogation for elucidating colon cancer tumorigenesis and identifying novel combination therapies

 
Terry Lechler, Ph.D.

Duke University Medical Center

Mechanism of asymmetric cell divisions and their role in tumor supression

  

* Alexander Minella, M.D.

Northwestern University Feinberg School of Medicine

Deregulated cell cycle controls in the pathogenesis of hematopoietic cancers

 

* Sohail Tavazoie M.D., Ph.D.

Rockefeller University 

Dissecting the mechanisms that regulate the expression of human metastasis suppressor microRNAs

Andrea Ventura, M.D., Ph.D.

Memorial Sloan Kettering Cancer Center

Functional analysis of the miR-17~92 family of oncogenic miRNA clusters

 

Bin Wang, Ph.D.

M.D. Anderson Cancer Center

Functional analysis of new regulatory components in BRCA1 signaling and tumor suppression

 

Zefeng Wang, Ph.D.

University of North Carolina at Chapel Hill

Engineering artificial splicing factors with designed specificities as new cancer treatments

 


 

* Translational Scholars

 

 

2008 KIMMEL SCHOLAR AWARDEES

 

Nabeel Bardeesy, Ph.D.

Massachusetts General Hospital 

Function of the WTX tumor suppressor

 

*Barbara Buttin, M.D.

Northwestern University

The role of synuclein-gamma (SNCG)in the carcinogenesis of uterine papillary serous carcinoma

Richard Gardner, Ph.D.

University of Washington

Understanding the roles of protein deubiquitination in chromatin regulation and other vital nuclear processes

 

* Ramiro Garzon, M.D.

Ohio State University

Epigenetic modulation of DNA methyltransferases by miR-29b: a paradigm for developing novel hypomethylating strategies in AML

 

* Roger Greenberg, M.D., Ph.D.

University of Pennylsvania School of Medicine

Control of homologous recombination at DNA double strand break sites by manipulating lysine-63-linked ubiquitin metabolism

 

Patrick Hu, M.D., Ph.D.

University of MIchigan

Novel regulators of FoxO tumor supressors

 
Tae Hoon Kim, Ph.D.

Yale University

Genome-wide analysis of chrom

  

Karen Liby, Ph.D.

Darthmouth Medical School

New drugs and drug combinations for the prevention and treatment of cancer

 

* Ingo Mellinghoff, M.D.

Memorial Sloan-Kettering Cancer Center

Overcoming PTEN-associated resistance of EGFR kinase

 

Raul Mostoslavsky, M.D., Ph.D.

Massachusetts General Hospital

The role of the SIRT6 chromatin factor in DNA repair and in metabolic homeostasis

 

Cathie Pfleger, Ph.D.

Mount Sinai School of Medicine

Identification and chracterization of mutations in non-tumor cells that promote metastasis

 

Jeroen Roose, Ph.D.

University of California, San Francisco

Increased RasGRP1 function leads to aberrantly sensitized Ras activation and development of T cell lymphomas in humans

 

Lanlan Shen, M.D., Ph.D.

University of Texas, M.D. Anderson Cancer Center

Epiteneticreprogramming in cancer

 

Hengbin Wang, Ph.D.

University of Alabama, Birmingham

Role of Ubp-M and H2A deubiquitination in breast cancer development


* Jen Jen Yeh, M.D.

University of North Carolina at Chapel Hill

Identification and validation of novel targets for the treatment of pancreativ cancer using a prognostic gene signature

 

Hang Yin, Ph.D.

University of Colorado, Boulder

Novel peptide probes to study the activation mechanism of the Epstein-Barr Virus latent membrane protein 1

 

 

* Translational Scholars 

 

 

2007 KIMMEL SCHOLAR AWARDEES

 

 

*Mary Armanios, M.D.

Kimmel Comprehensive Cancer Center at Johns Hopkins

Consequences of telomere shortening on stem cell compartments

 

Jennifer Cochran, Ph.D.

Stanford University

Molecular design and engineering of growth factor receptor antagonists for cancer therapy

 

*Patricia Dahia, M.D., Ph.D.

University of Texas, San Antonio

Energy Metabolism and Cancer

 

Konrad Hochedlinger, Ph.D.

Massachusetts General Hospital

Analysis of the transcription factor Sox2 in spermatogonial stem cells and germ cell cancer

 

Wendong Huang, Ph.D.

Beckman Research Institute of City of Hope

The role of FXR-dependent bile acid signaling in liver regeneration and hepatocarcinogenesis

 

Eric Lai, Ph.D.

Memorial Sloan-Kettering Cancer Center

Functional analysis of microRNA activity in Drosophila cancer models

 

*William Matsui, M.D.

Kimmel Comprehensive Cancer Center at Johns Hopkins

Stem cell regulatory pathways as therapeutic targets in multiple myeloma

 

Kathrin Plath, Ph.D.

University of California, Los Angeles School of Medicine

Function of histone modifications and their enzymes in cancer cells

 

*Sridhar Ramaswamy, M.D.

Massachusetts General Hospital

Creating bioactive feeders for cancer discovery

  

*David Solit, M.D.

Memorial Sloan-Kettering Cancer Center

Predictors of MEK dependence in RAS and BRAF mutant tumors

 

Wenyi Wei, Ph.D.

Beth Israel Deaconess Medical Center

Identification of novel regulatory mechanisms and substrates for Cdh1 and elucidation of its potential tumor suppressor function

 

Jing Yang, Ph.D.

University of California, San Diego

Dissecting the molecular basis of carcinoma metastasis

 

Angela Zarling, Ph.D.

University of Virginia

Targeting of tumor cells utilizing human lymphocytes engineered to express chimeric T-cell receptors specific for phosphorylated MHC-restricted antigens 

 

Rui Zhao, Ph.D.

University of Colorado at Denver

Targeting the Six1 transcriptional complexes for anti-cancer drug design

 

* Translational Scholars

2006 Kimmel Scholar Awardees

Thijn R. Brummelkamp, Ph.D.
Whitehead Institute for Biomedical Research
Functional characterization of the cancer genome

Jan A. Burger, M.D.
The University of Texas M.D. Anderson Cancer Center
Cross talk between the B-cell receptor and CXCR-4 chemokine receptors in chronic lymphocytic leukemia: a new role for ZAP-70

Shridar Ganesan, M.D.
Cancer Institute of New Jersey
Biology of human basal-like breast cancers

Or Gozani, M.D., Ph.D.
Stanford University
ING proteins: linking chromatin modulation to tumor suppression

Amy A. Kiger, Ph.D.
University of California
Roles and regulation of myotubularin-dependent phosphoinositide pathways in cellular differentiation

Andrew L. Kung, M.D., Ph.D.
Dana-Farber Cancer Institute
Tumor hypoxia: mechanisms of adaptation and opportunities for therapeutic targeting

Ming Lei, Ph.D.
University of Michigan
Structural studies of single-stranded telomeric DNA and its binding protein POT1

Loren Michel, M.D.
Washington University in St. Louis
Validating the Trop-2 receptor as a target for anti-cancer therapy

Yanhong Shi, Ph.D.
Beckman Research Institute, City of Hope National Medical Center
The role of nuclear receptor TLX signaling in brain tumors

Kimberly Stegmaier, M.D.
Dana-Farber Cancer Institute
Modulating the ‘undruggable’ oncoprotein with signature-based small molecule library screening

E. Alejandro Sweet-Cordero, M.D.
Stanford University
Functional genomic analysis ofoncogenic K-ras signaling

David Traver, Ph.D.
University of California
The role of Runx1 in normal and neoplastic hematopoiesis

Nicola Zanesi, Ph.D.
Ohio State University
Mouse models of the most common human cancers

Xianzheng Zhou, M.D., Ph.D.
The University of Minnesota
Adoptive T-Cell therapy of leukemia by the Sleeping Beauty transposon

Sandra S. Zinkel, M.D., Ph.D. 
Vanderbilt University
The role of proapoptotic BID in mediating apoptosis and the DNA damage response in myeloid homeostasis and leukemogenesis



2005 Kimmel Scholar Awardees

Iannis Aifantis, Ph.D.
University Of Chicago
Mechanisms of Notch-Induced T Cell Leukemia

Rami Aqeilan, Ph.D.
The Ohio State University Research Foundation
The Role of WWOX Tumor Suppressor Gene in Cancer

Catherine Bollard, M.D.
Baylor College of Medicine
Overcoming Tumor Immune Evasion Strategies in Lymphoma

Ruben Carrasco, M.D., Ph.D.
Dana-Farber Cancer Institute
Genetic Models and Translational Studies of Multiple Myeloma

Sandy Chang, M.D., Ph.D.
University of Texas M.D. Anderson Cancer Center
Molecular Mechanisms Controlling the Alternative Lengthening of Telomeres Pathway

Patricia Ernst, Ph.D.
Dartmouth College
MII-Dependent Pathways in Normal and Leukemic Hematopoiesis

Dmitry Fyodorov, Ph.D.
Albert Einstein College ofMedicine
Biochemistry and Genetics of Chromatin Assembly

Lucy Godley, M.D., Ph.D.
University Of Chicago
The Role Of DNMT3B in Mediating The Abnormal DNA Methylation Patterns in Cancer Cells

Johanna Joyce, Ph.D.
Memorial Sloan Kettering Cancer Center
Genetic Analysis of the Cysteine Cathepsin Family of Proteases During Multistage Tumor Development

Chang Kim, Ph.D.
Purdue University
Identification of Trafficking Signals Important for Cancer Cell Interaction ith Regulatory T Cells

Anthony Letai, M.D., Ph.D.
Dana-Farber Cancer Institute
Targeting Apoptotic Defects in Cancer

Gary Luker, M.D.
University Of Michigan
Imaging CXCR4 in Primary and Metastatic Breast Cancer

Toru Nakamura, Ph.D.
University of Illinois at Chicago
Roles of Checkpoint Proteins and Chromatin Modifications in Genome Stability, DNA Repair and Telomere Maintenance

Joel Pomerantz, Ph.D.
The Johns Hopkins University School of Medicine
The Identification of Targets for the Treatment of NF-Kb-DependentCancers

David Watkins, M.D., Ph.D.
The Johns Hopkins University School of Medicine
Basic and Preclinical Investigation of Aberrant Hedgehog Signaling In Cancer

 

2004 Kimmel Scholar Awardees

Ivan Borrello, M.D.
SidneyKimmel Cancer Institute, Johns Hopkins University
Strategies to Enhance Tumor-Specific Immunotherapy in Multiple Myeloma

Scott Briggs, Ph.D.
Purdue University
Functional Characterization of The Multiple Myeloma SET Domain Protein (MMSET)

George Calin, M.D., Ph.D.
Kimmel Cancer Center, Thomas Jefferson University
The Role of Micro RNAs In Human Cancer Development

Diego Castrillon, M.D., Ph.D.
University of Texas, Southwestern Medical Center (Dallas)
Genetic Model Systems and Translational Studies of Endometrial Cancer

James Chen, Ph.D.
Stanford University School of Medicine
Chemical and Genetic Studies of the Hedgehog Pathway

David Ferguson, M.D., Ph.D.
University Of Michigan, Ann Arbor
Genomic Instability in Cancer Mechanisms of Gene Amplification and Roles Of Mre11

Daniel Kamei, Ph.D.
University Of California, Los Angeles
Increasing the Half-Lives of Angiogenesis Inhibitors Using Systems-Level Analyses

Clara Kielkopf, Ph.D.
Johns Hopkins University
Structural Basis Of Normal Pre-Mrna Splice Site Recognition and Its Dysfunction In Neoplasia

Harmet Malik, Ph.D.
Fred Hutchinson Cancer Research Center
Is Genetic Conflict Responsible for Centromere Complexity?

Jeffrey Rathmell, Ph.D.
Duke University Medical Center
Cell Survival and Glucose Uptake in Cancer and Autoimmunity

Jeremy Rich, M.D.
Duke University Medical Center
Transforming Growth Factor Beta Signaling and Targeting In Malignant Gliomas

Brian Schaefer, Ph.D.
Uniformed Services University of The Health Sciences
Role Of NF-Kb Signaling Intermediates In The Etiology Of MALT Lymphoma

Sheila Stewart, Ph.D.
Washington University
Molecular Mechanisms of Cellular Immortality

Kwok-Kin Wong, M.D., Ph.D.
Dana Farber Cancer Institute
The Genetic Role of Telomere Dynamics and DNA Damage Response in Cancer And Aging

Yihua Yu, Ph.D.
University Of Utah
An Integrated Docking/Imaging Device for Cancer Radioimmunotherapy

2003 Kimmel Scholar Awardees

Joanne Chan, Ph.D.
Children's Hospital, Boston
Genetic dissection of angiogenesis in the zebrafish

Nancy DeMore, M.D.
University of North Carolina at Chapel Hill
Molecular mechanisms controlling human tumor dormancy

Nicholas Gaiano, Ph.D.
Johns Hopkins University
The regulation of neural stem cell proliferation by notch and FGF signaling

David Jeruzalmi, Ph.D.
Harvard University
Structure and function of the mini-chromosome maintenance (MCM) assembly

Ann L. Kirchmaier, Ph.D.
Purdue University
Epigenetic regulation of Epstein-Barr viralgene expression

Motonari Kondo, M.D., Ph.D.
Duke University
Lineage infidelity: relationship between plasticity of lymphoid progenitors and leukemogenesis

Sang Eun Lee, Ph.D.
University of Texas, San Antonio
Role of chromatin remodeler in repair of damaged DNA

Mark Levis, M.D., Ph.D.
Johns Hopkins University
Targeting FLT3 as a novel, specific therapy for leukemia

Linda Liau, M.D., Ph.D.
University of California, Los Angeles
Characterization of GDOX, a novel putative oncogene preferentially expressed in human glioma

Ari Melnick, M.D.
Albert Einstein College of Medicine
Development of structure-guided molecular targeted transcription therapy for b-cell lymphoma

Akhilesh Pandey, M.D., Ph.D.
Johns Hopkins University School of Medicine
Molecular dissection of EGF receptor signal transduction

Roberto Pili, M.D.
Johns Hopkins University
Novel combination therapy targeting tumor angiogenesis with chromatin remodeling agents

Norman Sharpless, M.D.
University of North Carolina at Chapel Hill
The regulation of the tumor suppressor p16INK4a in cancer and aging

Said Sif, Ph.D.
Ohio State University
Role of histone methyltransferase-containing human SWI/SNF complexes in cancer

Srinivasa Srinivasula, Ph.D.
Thomas Jefferson University
Characterization of caspase linker domain(s)

Robert Wechsler-Reya, Ph.D.
Duke University
The molecular basis of childhood brain tumors